India is on the radar for the
US-based philanthropic organization and will certainly benefit
from the rolling out of mammoth funding initiatives in vaccine
development and delivery
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Speaking at the World Economic Forum at Davos last year,
Microsoft founder and philanthropist, Bill Gates, called
upon the global community and announced that in the coming
decade, the Bill and Melinda Gates Foundation would donate a
whooping sum of $10 billion towards the development and delivery
of vaccines to the developing nations of the world. Defining 2011 to
2020, as the decade for vaccines and polio immunization, Mr Gates
further added that through these grants, he is looking at creating a
drastic drop in child mortality due to diseases like malaria,
tuberculosis, pneumonia and diarrhea for which vaccines are yet to be
made available. He further said that vaccines for these diseases would
save around eight million children by the end of 2020.
Mission India
Amongst developing nations, India stands as a priority region for the
foundation. As of December 2010, the foundation committed approximately
$1 billion for health projects in India. The Gates Foundation works on
a range of health and development efforts in India, including
immunization, maternal and child health, family planning, HIV/AIDS, TB,
water and sanitation efforts and agricultural development.
Speaking to BioSpectrum about the foundation's funding initiatives in
the country, Mr Ashok Alexander, India Country Office, Bill &
Melinda Gates Foundation, says, “Though statistics in India reveal that
in 2008, approximately 54 percent of children in India received
full set of vaccines as recommended in India's national immunization
programme, a lot needs to be done. Grants include support to polio
eradication efforts through the Global Polio Eradication Initiative
(GPEI), the introduction of hepatitis B vaccine through the GAVI
Alliance and late-stage clinical development of a new rotavirus vaccine
to reduce severe diarrhea in young children.” The Gates Foundation also
supported the development of the bivalent oral polio vaccine, which was
introduced last year in India and has helped reduce cases of polio
virus types 1 and 3 to record lows. “India has made remarkable progress
against polio, however, outbreaks still persist. Until eradication is
achieved, the various program activities have to be continued to end
this disease,” adds Mr Alexander.
Diseases like pneumonia and diarrhea have off-late been of growing
interest to the foundation. Today, in India, pneumonia and diarroheal
diseases like rotavirus, currently, account for approximately one-third
of all deaths among Indian children younger than five years of age. “As
the world's leader in vaccine manufacturing, India has an unparalleled
ability to develop new, safe and effective vaccines and make them
available to Indian children at affordable prices. Through our grantee
PATH Vaccine Solutions, the Gates Foundation is working with the Serum
Institute of India and Bharat Biotech to support the development of
innovative, high-quality, low cost vaccines for rotavirus, which causes
severe diarrhea, and pneumococcal disease,” says Mr Alexander.
Partnerships
Since its inception, the foundation has been partnering with national
and state governments, scientists, manufacturers, NGO and community
leaders in exploring ideas on delivering vaccines and other
interventions that benefit Indians and others worldwide. “One of our
strongest partnerships in India is with the government of Bihar. Along
with the state governments and leading domestic and international NGOs,
we recently launched a five-year, $80 million portfolio of grants to
address maternal and child health issues,” adds Mr Alexander.
Bill and Melinda Gates visited India in March 2011 and met policy
makers, non-government partners, business and community leaders, and
public health figures (celebrities) urging stakeholders to intensify
progress on vaccinating its populace, especially children. During their
visit, Bill and Melinda Gates announced that they would pool in grants
to fund late stage clinical trials to Pune-based Serum Institute of
India and Hyderabad-based, Bharat Biotech International, for pneumonia
and rotavirus vaccines. Though the parties were reluctant to
reveal the exact value of the grants, reports have highlighted that
the foundation is looking at granting around $30 million for late
stage clinical trials of rotavirus vaccines.
Looking Forward
Giving an overall perspective, the Gates Foundation believes that in
the avenue of vaccines, India still faces some critical challenges like
scaling up routine immunization and access to newer vaccines, such as
for measles and certain types of diarrhea and pneumonia. Partnerships
with local stakeholders will be a springboard to tackle this challenge.
“The foundation will continue to work with the Indian government and
all of our local partners to find solutions to scaling up routine
immunization and access to vaccines. This includes support for research
that reinforces the lifesaving value and cost-effectiveness of these
vaccines; continued work with Indian researchers and companies to
produce new, safe and less expensive vaccines and partnerships with
governmental and non-governmental groups,” concludes Mr Alexander.
Nayantara Som in Mumbai