Ocimum
creates niche with bioinformatics services
Ocimum Biosolutions is
an integrated life sciences R&D, enabling companies providing
focused solutions for different steps of the genomics process chain.
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After joining hands with Gene Logic, Ocimum Biosolutions offers a
strong bioresearch portfolio including knowledge bases in genomics and
solutions in toxicogenomics, pharmacogenomics and clinical genomics.
Through the BioIT division, Ocimum provides expertly trained lab
information management solutions for life sciences, niche
bioinformatics services and products for genomic research such as gene
expression analysis, advanced statistical analysis, gene function
analysis, genome annotation, sequence comparison and EST analysis. The
BioMolecules division produces microarrays and oligonucleotides. The
Microarray division has been acquired from MWG Biotech, Germany and
produces catalog OciChip arrays, custom OciChip arrays and offers
microarray hybridization services. The oligonucleotides division, which
has been acquired from Isogen Lifescience, Netherlands, makes standard
and modified DNA, RNA oligonucleotides.
Ocimum Biosolutions has recently introduced a microarray-based test
(research use only) for the latest version of the H1N1 flu. The
microarray was developed on Ocimum’s custom OciChip array
platform three years ago when the first case of the avian flu outbreak
occurred. This has been updated with the latest sequence
information posted last week and the probes have been
redesigned. This test will be available for use after
completion of validation. Ocimum also provides an
RT-PCR-based molecular diagnostic assay for use in India and Asia.
In line with its strategic objective to build a global network of
service centers in close proximity to leading genomics researchers,
Ocimum Biosolutions have launched genomic services on Affymetrix
platform from Europe. Initially Ocimum will service gene expression
studies on the Affymetrix platform from its facility at IJsselstein,
The Netherlands. Within a couple of months, it will launch the entire
bouquet of services from its IJsselstein facility.
The company has been awarded with two US patents one for its
proprietary system and method for determining matching patterns within
gene expression data and determining renal toxins and one US patent for
molecular toxicology modeling to elucidate global changes in gene
expression and identification of toxicity markers in tissues or cells
exposed to a known renal toxin. The invention includes a database of
genes characterized by toxin-induced differential expression that is
designed for use with microarrays and other solid-phase
probes.