BioSpectrum Awards 2003 - State of the year

12 December 2003 | News

State of the year

State of the year

Andhra Pradesh

The Biotech Building Block

One of the most common grouse of entrepreneurs is that the governments are not doing enough to fuel their passion. This is a problem akin to all industries. Biotech is no different. But here is one state, which has made a difference. Be it small or big, new or old, states have begun the exercise to promote biotech. States are vying with each other for a share in attracting companies to their respective states. The reason: Andhra Pradesh has demonstrated that biotech can be groomed into a booming opportunity.

A recent BioSpectrum-ABLE Top20 survey shows that the South has the largest share of business representation with about 39 percent hold in the Indian biotech industry. The total revenues generated by the South-based firms were Rs 899 crore. Out of this, business generated by companies in Karnataka was Rs 500 crore and that of Andhra Pradesh was in excess of Rs 200 crore. Though Karnataka may look bigger than Andhra Pradesh purely on this figure, the Biocon Group with total revenues of Rs 285 crore alone is the biggest contributor. It has over 55 percent of total contribution from the companies in Karnataka. Discount Biocon and it would be completely in favor of Andhra Pradesh.

Many states would not agree in public that Andhra Pradesh is their role model. But the reality is that Andhra is leading the biotech revolution of the country by example. "The birth of a biotech cluster" reported The Financial Times (London) in its 14 August 2003 report on Andhra Pradesh. No doubt, it is the life sciences hotspot. It is a happening state. If not, why would Ranbaxy go to Andhra Pradesh? Several others like Astra Zeneca, Pfizer and Chemical Diversity, Genoexpression, Transzyme have agreed to start their biochemical R&D operations and contract research in ICICI Knowledge Park and SP Biotech park. Some of these deals are expected to be completed soon.

More corporate than the corporates

Andhra definitely has an unparalleled mindshare. Thanks to the efforts of the state government. The state government is the inducing factor. There is a corporate or business like approach. The team responsible for driving the initiatives may not be sitting in the most elegant of buildings like the modern corporates, but the team is much sharper—in attitude, focus and decision making. The team defies the typecast bureaucratic image. It is much more approachable and responsive. As reporters we have experienced a much easier access vis-à-vis even some of the top named companies with great corporate governance.

At the outset, one would not find these typical designated persons like chairman, CEO, and COO. But the team operates those responsibilities with ease. If permitted to map the organization tree of the government team, responsible for the biotech business of the state, it would read: Chief minister N Chandrababu Naidu as chairman; BP Acharya (secretary, industries and commerce department, Andhra Pradesh) as CEO; and D Nalini Mohan (additional secretary and director biotech) as the COO. Chief minister Chandrababu Naidu is a visionary. People like Dr Manju Sharma, secretary, DBT, feel that Chandrababu Naidu is great favorite of the scientific community and he prevails in decision making. Acharya and Mohan not only pair up very well, but also complement each other. While Acharya's strengths lie is thinking through, Mohan is a biologist himself. So it is not surprising to find Acharya and Mohan speaking business and biotech with ease.

Added to that, the state government has a think tank. Dr Manju Sharma, secretary, DBT, Dr D Balasubramanian, head of research, LV Prasad Eye Institute, Dr MV Rao, former VC, Andhra Pradesh Agriculture University, Dr Lalji Singh, director, CCMB, Dr Syed Hasnain, director, Centre for DNA Fingerprinting and Diagnostics, S Dhawan, representative, Biotech Park Joint Venture Company and Utkarsh Palnitkar, consultant, Ernst & Young, are its members. They come from diverse fields and with varying expertise and lend a hand in shaping the biotech development in the state. It is this approach that the state of Andhra Pradesh follows that facilitates the development of the biotech business.

Marketing model

Success of any business is a conjunction of good products and effective marketing. Andhra Pradesh has the attitude of a business conglomerate. A quick analogy will show that the state government is the platform maker. The platform is the building block to build biotech industry. It is the "Intel Inside" for biotech. In fact the state has all the components that make it a quality platform. The state has a biotechnology policy, APIDC Venture Capital Ltd, a joint venture between the Andhra Pradesh Industrial Development Corporation and Dynam Venture East of USA, which has been providing venture capital to biotech start-ups. It has also an integrated IPR facilitating cell at ICICI Knowledge Park established is association with CII. This is to cater to the growing demands of the industries in Andhra Pradesh for patent search and analysis, patentability advisory services, IPR awareness and training.

The list can stretch. The difference the state brings in business parlance is the early bird advantage. It has done all this before any other state. It is a strong marketing machine too. It understands the importance of brand building, selling, and customer care, not just facilitating the growth. Take for instance, Genome Valley. It is India's first state-of-the-art biotech cluster providing solid infrastructure to over 100 biotech companies. Keep aside the features like it is a natural cluster for biotech research, training, collaboration and manufacturing activities, spread over 600 sq. km. It would be more important to note here that the state has applied for the trademark. Steps like these demonstrate not only its smartness, but also its depth in understanding about how to build a brand.

The state also realizes the importance of strategic alliances. For instance, it signed an agreement with Thailand to mutually promote biotech through collaboration in research and exchange of scientists and teaching professionals. This alliance would be beneficial in the area of marine biotechnology and biotech applications for aquaculture and tropical medicine. The agreement with Iowa State of USA is to leverage agribiotech and bio-medical research. Take another case, it tied up with Research Triangle Park of North Carolina in February 2002. Because of this equation, companies like CiVentiChem, a contract research and drug-discovery support company, and Kard Scientific Inc. of Cambridge, USA have set shop in Genome Valley. There are hardly a handful of states seeing the importance of strategic alliances.

Another thing the state is doing is facilitating networking. It has decided on two features—Biotec International, a show to be held once in two years, and BioAsia an annual premier event. The first version of BioAsia is scheduled for February 2004. Acharya said, "The series of events will enable the industry to have a platform to understand the issues and deliberate and also showcase each other's strengths." Such conferences have proved to serve as an excellent "industry-academia-global" networking platform.

What's next?

What most companies admire about the state is its initiative in setting up APIDC Venture Capital Ltd. Its "Biotechnology Venture Fund" is India's first national fund focused on biotechnology companies. It has already funded to a tune of Rs 8.1 crore in three companies and targets a Rs 150 crore corpus.

While most states are still talking about wooing investors and trying to build infrastructure or drafting biotech policies, Andhra has already begun to think on the next step forward. How to make Andhra a global vaccines supplier? How to attract a few world leaders in the biotech sector to set shop in the parks? Set up an animal research and testing center. Start the International Institute of Life Sciences. All these, to take form, may take time. Nevertheless, it is the pioneer of a model that today others can replicate. That is why industry leader Kiran Mazumdar-Shaw does not hesitate in saying "The combination of Karnataka's entrepreneurship and Andhra government's vision, strategic direction, and support give India a very strong profile."

Ch. Srinivas Rao

"We are setting up standards with world class infrastructure and a long term policy for making AP the #1 destination for investments from all over the world."

Interested in knowing what is happening in Andhra Pradesh! BioSpectrum could have written on the biotech activity in the state. But we decided that this information, if it comes from the horse's mouth, will be even more interesting to read. We sent a detailed questionnaire to Chief Minister N Chandrababu Naidu and he responded to the same. Here is what Naidu has to say on the state's biotech activities, initiatives, plans and vision.

What is your vision for Andhra Pradesh with reference to the biotech/life sciences sector?

My vision for Andhra Pradesh with reference to biotech and life sciences sector is that a common man should get the benefits of new technologies emerging in these fields. My vision is to provide a disease-free and healthy society by using modern technologies and we are working towards that. For instance, we are establishing International Institute of Life Sciences in Hyderabad, involving the leading biotech and life sciences industries in the State.

We are developing centers-of-excellence in different branches of biotechnology viz. for agri and veterinary biotechnology in Acharya NG Ranga University, an agribiotech incubator in ICRISAT, a marine resource development center in association with Andhra Pradesh University and a pharma biotech hub in SP Biotech Park and ICICI Knowledge Park in Genome Valley near Hyderabad. Through such initiatives, we envision developing the state of AP into a biotechnology state of the country.

When and how did Andhra Pradesh embark on attracting investments in biotechnology?

Andhra Pradesh has a very strong pharmaceutical industry. It is the bulk drug capital of the country. So when the Government of Andhra Pradesh started to emphasize on biotechnology, several industry leaders started looking towards Andhra Pradesh and Hyderabad in particular. The state has been attracting investments in biotechnology for the last seven to eight years and the investments have picked up in the last couple of years.

What are the short term and long term strategies to make AP a leader in biotechnology?

Andhra Pradesh is the first state in the country to have an exclusive policy for biotechnology in the year 2001. We have announced the policy framework and clear strategies have been worked out. The short term strategies are projecting the strengths of the state, especially the locational advantage of Hyderabad, the strong presence of world class research institutes like CCMB, CDFD and IICT, the availability of a strong pool of trained and scientific manpower, the recently developed ICICI Knowledge Park and SP Biotech Park and a proactive and environment friendly Government Policy.

Among the other strategies to make AP a leader in biotechnology, we have created a brand name called "Genome Valley" and it is widely popular all over the world. We are setting up standards with world class infrastructure and a long term policy for making AP the #1 destination for investments from all over the world. We have created an enabling environment for establishing the biotech industry. We have a single window clearance system for hassle free licensing and approvals. We participate in the international and national exhibitions, conferences and demonstrate our strengths and invite foreign participation and collaboration into Andhra Pradesh. We are liberalizing the labor laws to match the requirements of the industry.

Has the State Government identified specific sectors to leverage the existing strengths in AP and leapfrog in biotech?

The AP government has been encouraging pharma and biotech sectors to leverage the existing strengths in AP. Vaccines and recombinant DNA products in health care, nutraceuticals and medicinal plant formulations are some of the areas that have been identified as key sectors for growth and long-term development. This apart, contract research and clinical trials also have good promise.

The APIDC-VCL is a path-breaking initiative by AP to provide the much needed "seed funds" for biotech entrepreneurs. Will the corpus be increased if the demand from entrepreneurs increases tremendously?

APIDC-VCL is the first of its kind in the country. Government of Andhra Pradesh has analyzed that the most crucial input in starting a new venture is the VC funding. In order to kick start the biotech industry, especially startups, the APIDC-VCL endeavor is vital. The corpus is swelling every day and as of now it is targeted to mop up about Rs 150 crore. Apart from the AP government, Andhra Bank, LIC, GIC, PNB and others are participating in this VC Fund.

What are the Government's plans to provide the latest infrastructure and incubator facilities to biotech entrepreneurs?

The Government of Andhra Pradesh has special plans to provide the latest infrastructure in the form of uninterrupted water and electricity supplies to the Biotech and Knowledge Parks. A dedicated sub-station has been erected in the Genome Valley for uninterrupted electricity. Fast track roads have been laid connecting the Genome Valley to other parts of the city. India's first biotech incubator is being established in SP Biotech Park in Genome Valley with an outlay of Rs 22.50 crore in association with DBT and IICT. The incubator offers the latest state-of-the-art facilities for start-up and existing biotech companies and entrepreneurs to try out their new technologies and processes which otherwise would become very difficult to do. The Government is investing huge amounts on all the infrastructure. A National Animal Resource Testing facility is also planned in association with ICMR and National Institutes of Health and an area of 100 acres has been earmarked for this purpose in Genome Valley. An agribiotech incubator is coming up in ICRISAT exclusively for developing new technologies for sustainable agriculture. It will facilitate in producing new crops and varieties for food security and for increasing the nutritional value.

What are the fiscal and other incentives available to potential biotech entrepreneurs in AP?

There are a number of incentives available to potential entrepreneurs in Andhra Pradesh. There is 25 percent capital subsidy in the cost of the land for the biotech parks, and a rebate in the land cost at the rate of Rs 30,000 for every job created in bioinformatics and other related fields in the parks and a concessional sales tax of only 1 percent as against 12-14 percent outside the park areas. The other incentives available to potential biotech entrepreneurs in AP include provision of water supply and power supply up to the doorstep and excellent roads. A residential accommodation proposal for the personnel working in Genome Valley at concessional rate has also been initiated recently. The government has created an IPR facilitation cell for helping companies in their patenting and other aspects as well as a virtual library and documentation center in ICICI Knowledge Park.

Many states seem to be competing with each other to attract biotech entrepreneurs? Is such competition desirable and healthy?

In a growing economy, competition is unavoidable. Irrespective of where the investment comes from, India is developing and marching ahead in the field of biotechnology. But the investors will always look for the best state on "good governance" and if healthy competition exists, it will boost the industrial growth and help the country ultimately.

Which are the most promising startups and technologies emerging in the state?

There are many startups and technologies in biotechnology. Matrix Laboratories, GVK Bio-Sciences, Bio-Serve Biotechnologies, Krebs Biochemicals, Indigene Pharma, etc. are a few start-ups with their new technologies and international partners located in the Knowledge Park. The Biotech Park has companies like Genotex, KCP Biotech, Ocimum, Jasmine, Aktiva Biotech and Sandor. These are all startups with good promise. Many companies have anti-cancer and anti-AIDS technologies and products like diagnostic kits are being proposed to be manufactured in Hyderabad.

Will you push for a National Biotechnology Policy and a National Biotech Venture Fund to give fillip to this sector?

A biotechnology VC Fund at national level is a necessity for India. We will also strive to get a National Biotechnology Policy.

High quality education is a key factor in biotech. AP has a number of top quality education centers. Any plans to supplement these efforts to cater to the future needs?

We are at present strengthening the existing training and educational institutions in the state. We are planning to set up one Marine Bioresources Development Center in Visakhapatnam. While an agribiotech incubator is coming up in ICRISAT campus, National Animal Resource Testing facility is being set up in collaboration with ICMR/NIH at Genome Valley.

Are there any plans to ensure that the private sector educational institutions adhere to certain minimum standards?

We have an active private sector in the state. We encourage public-private and private sector participation models in biotech education and industry. Quality standards are maintained in education and training. Genome Valley is emerging as a quality standard certification agency for biotech in the state.

Do you have any specific projects to ensure that some of the benefits of modern biotechnology address the larger social and health issues confronting people in tackling diseases like typhoid, cholera and malaria?

Our Government is committed to health for all. Health is identified as one of the important thrust areas. Immunization programme is very successful in the state.

We are marching towards vaccines for cholera, typhoid and other communicable diseases. Hyderabad is emerging as the vaccines' capital of the country. We have leading developers and manufacturers like Biological E, Bharat Biotech and Shantha Biotech here.

What would you like Andhra Pradesh to be related with—meaning what should the recall value of the State be?

I want AP to be #1 in biotech. That is our goal. I think we are marching ahead.

Who are the members of your biotech team? And to whom should the credit go in making biotech successful in AP?

Government is proactive and responsive. It is a team effort.

 

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