Tuesday, 27 September 2022

Tata Memorial’s clinical trial offers new hope to breast cancer patients

12 September 2022 | News

Injection of a commonly used drug around the tumour on the operating table, just prior to surgery shows significant and substantial increase in cure rates and survival

image credit- shutterstock

image credit- shutterstock

Dr Rajendra Badwe, Director of Mumbai-based Tata Memorial Centre, presented the results of a landmark multi-centre Indian breast cancer study at the ongoing European Society of Medical Oncology (ESMO) Congress in Paris, one of the most prestigious cancer conferences in the world held annually in Europe.

The trial in women undergoing breast cancer surgery involved the injection of a commonly used drug around the tumor on the operating table, just prior to surgery. The results of this trial show that this simple, low-cost intervention significantly and substantially increases the cure rates and survival with a benefit that is ongoing for several years after surgery.

The injection requires no additional expertise, is inexpensive, and can result in saving up to 100,000 lives annually globally. These benefits are substantial and were achieved with an intervention the cost of which was less than Rs 100 per patient. For comparison, benefits of far lesser magnitude have been achieved in early breast cancer patients by much more expensive, targeted drugs which cost more than ten lakhs per patient.

Dr Badwe commented, "This is the first study of its kind globally, that has shown a sizable benefit by single intervention prior to surgery.  If implemented across the world, it has the capability to save over 100,000 lives annually.  For scientists, it opens the window of peri-operative intervention to modulate the environment of cancer in such a way as to prevent its deleterious reaction to the act of surgery. Evolving low-cost interventions for cancer has been a mission of Tata Memorial Centre and Department of Atomic Energy for the benefit of Indian and global population and this study, supported by the Department of Atomic Energy, is a major step towards Atma nirbhar Bharat."

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